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CD3 epsilon Antibody (APA1/1), Janelia Fluor™ 549, Novus Biologicals™
SDP

Catalog No. NBP13426549 Shop All R&D Systems Products
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NBP13426549 0.1 mL
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Catalog No. NBP13426549 Supplier Novus Biologicals Supplier No. NBP130426JF549
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Mouse Monoclonal Antibody

CD3 epsilon Monoclonal specifically detects CD3 epsilon in Human, Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen.

Specifications

Antigen CD3epsilon
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone APA1/1
Conjugate Janelia Fluor 549
Dilution Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE
Gene Symbols CD3E
Host Species Mouse
Immunogen Purified human CD3 proteins isolated from thymus
Purification Method Protein A purified
Quantity 0.1 mL
Research Discipline Adaptive Immunity, Apoptosis, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Lines, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 916
Test Specificity The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
Target Species Human, Mouse
Content And Storage Store at 4°C in the dark.
Form Purified
Isotype IgG1
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