CD3 epsilon Antibody - BSA Free, Novus Biologicals™

Catalog No.	Quantity
NBP233116	0.1 mg

Catalog No. NBP233116 Supplier Novus Biologicals Supplier No. NBP233116

Description

Rabbit Polyclonal Antibody

CD3 epsilon Polyclonal specifically detects CD3 epsilon in Human, Rat, Primate samples. It is validated for Western Blot, Immunohistochemistry, CyTOF-ready.

Specifications

• Antigen: CD3 epsilon
• Applications: Western Blot, CyTOF, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
• Classification: Polyclonal
• Concentration: 1.0 mg/mL
• Conjugate: Unconjugated
• Dilution: Western Blot 1 - 2 ug/mL, CyTOF-ready
• Formulation: 10 mM PBS with 0.05% Sodium Azide
• Gene Alias: CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE
• Gene Symbols: CD3E
• Host Species: Rabbit
• Immunogen: A synthetic peptide aa156-168 (ERPPPVPNPDYEP) from human CD3 epsilon (Uniprot: P07766)
• Molecular Weight of Antigen: 23 kDa
• Purification Method: Protein A purified
• Quantity: 0.1 mg
• Regulatory Status: RUO
• Research Discipline: Adaptive Immunity, Apoptosis, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Lines, Stem Cell Markers
• Primary or Secondary: Primary
• Gene ID (Entrez): 916
• Test Specificity: Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
• Target Species: Human, Mouse, Rat, Pig, Amphibian, Bovine, Canine, Chicken, Equine, Feline, Guinea Pig, Hamster, Other, Primate
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Form: Purified
• Isotype: IgG

For Research Use Only