CD3 epsilon Antibody - BSA Free, Novus Biologicals™

Rabbit Polyclonal Antibody

Supplier:  Novus Biologicals NBP233116

Catalog No. NBP233116

Description

CD3 epsilon Polyclonal specifically detects CD3 epsilon in Human, Rat, Primate samples. It is validated for Western Blot, Immunohistochemistry, CyTOF-ready.

Specifications

• Antigen: CD3 epsilon
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: 10 mM PBS with 0.05% Sodium Azide
• Gene Symbols: CD3E
• Immunogen: A synthetic peptide aa156-168 (ERPPPVPNPDYEP) from human CD3 epsilon (Uniprot: P07766)
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG

• Applications: Western Blot, CyTOF, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
• Concentration: 1.0 mg/mL
• Dilution: Western Blot 1 - 2 ug/mL, CyTOF-ready
• Gene Alias: CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE
• Host Species: Rabbit
• Molecular Weight of Antigen: 23 kDa
• Quantity: 0.1 mg
• Research Discipline: Adaptive Immunity, Apoptosis, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Lines, Stem Cell Markers
• Gene ID (Entrez): 916
• Target Species: Human, Mouse, Rat, Pig, Amphibian, Bovine, Canine, Chicken, Equine, Feline, Guinea Pig, Hamster, Other, Primate
• Form: Purified

For Research Use Only