CD3 epsilon Antibody (RIV9), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2448800.2MG

Catalog No. NBP24488002

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

CD3 epsilon Monoclonal antibody specifically detects CD3 epsilon in Human, Mouse, Rat samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

• Antigen: CD3 epsilon
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 1 - 2 ug/ml
• Gene Alias: CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE
• Host Species: Mouse
• Molecular Weight of Antigen: 20 kDa
• Quantity: 0.2 mg
• Research Discipline: Adaptive Immunity, Apoptosis, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Lines, Stem Cell Markers
• Gene ID (Entrez): 916
• Target Species: Human, Mouse, Rat
• Form: Purified

• Applications: Flow Cytometry, Immunofluorescence
• Clone: RIV9
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: CD3E
• Immunogen: Human peripheral lymphocytes
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Reacts with five invariable CD3 chains (designated as and ) with molecular weight ranging from 16-28kDa. It is found on all mature T-lymphocytes, NK, T-cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. It is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. This MAb is particularly useful for induction of T cell activation in vitro and in vivo due to its unusual IgG3 isotype.
• Content And Storage: Store at 4C.
• Isotype: IgG3 κ

For Research Use Only