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CD30/TNFRSF8 Antibody (Ki-1/1505R), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NP247A30 Shop All R&D Systems Products
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NP247A30 0.1 mL
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Catalog No. NP247A30 Supplier Novus Biologicals Supplier No. NBP254557AF350
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Description

Rabbit Monoclonal Antibody

CD30/TNFRSF8 Monoclonal specifically detects CD30/TNFRSF8 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen CD30/TNFRSF8
Applications Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone Ki-1/1505R
Conjugate Alexa Fluor 350
Dilution Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8
Gene Symbols TNFRSF8
Host Species Rabbit
Immunogen Recombinant human full-length CD30/TNFRSF8 protein (Uniprot: P28908)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 943
Test Specificity Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkins disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This monoclonal antibody distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG
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