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CD31 Monoclonal Antibody (WM59), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA126196

Catalog No. PIMA126196

  • $473.65 / Each of 1

    Save 16%

    Reg : $562.00

    The following deviations and disclosures may produce prices below stated discounts but will not trigger price reductions: Price shown reflects a temporary, promotional price reduction. No other purchase or commercial obligation required to receive the reduced price. Price may change at any time. Promotional price valid on web orders only. Your contract pricing may differ. Other exclusions apply.
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Description

Description

In FACS use 10 μL of the suggested working dilution to label 10^6 cels in 100 μL. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD31
Monoclonal
1 mg/mL
PBS with 0.09% sodium azide
P16284, Q08481
Pecam1
Human CD31
100 μg
Primary
Cynomolgus Monkey, Human, Mouse, Non-human Primate, Rhesus Monkey
Antibody
IgG1
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Free Floating), Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
WM59
Unconjugated
Pecam1
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Mouse
Protein G
RUO
102117792, 18613, 5175, 718302
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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