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CD31/PECAM-1 Antibody (SPM122), Biotin, Novus Biologicals™
SDP

Catalog No. NBP234732B Shop All R&D Systems Products
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NBP234732B 0.1 mL
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Catalog No. NBP234732B Supplier Novus Biologicals Supplier No. NBP234732B
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Description

Mouse Monoclonal Antibody

CD31/PECAM-1 Monoclonal specifically detects CD31/PECAM-1 in Human, Cynomolgus Monkey, Rabbit, Porcine (Negative), Rat (Negative) samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen CD31/PECAM-1
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone SPM122
Conjugate Biotin
Dilution Western Blot, Flow Cytometry, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA′, PECA1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet endothelial cell adhesion molecule-1, platelet/endothelial cell adhesion molecule
Gene Symbols PECAM1
Host Species Mouse
Immunogen This CD31/PECAM-1 Antibody (SPM122) was developed against a membrane preparation of a spleen from a patient with hairy cell leukemia.
Molecular Weight of Antigen 82.5 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Angiogenesis, Cancer, Cellular Markers, Cytoskeleton Markers, Embryonic Stem Cell Markers, Endothelial Cell Markers, Extracellular Matrix, Hematopoietic Stem Cell Markers, Immunology, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Signal Transduction, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 5175
Test Specificity CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 monoclonal antibody reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Target Species Human, Cynomolgus Monkey, Rabbit, Porcine (Negative), Rat (Negative)
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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