| Antigen |
CD34 |
| Applications |
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) |
| Classification |
Monoclonal |
| Clone |
HPCA1/1806R |
| Conjugate |
DyLight 594 |
| Dilution |
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin |
| Formulation |
50mM Sodium Borate with 0.05% Sodium Azide |
| Gene Alias |
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule |
| Gene Symbols |
CD34 |
| Host Species |
Rabbit |
| Immunogen |
Recombinant full-length human CD34 protein (Uniprot: P28906) |
| Purification Method |
Protein A or G purified |
| Quantity |
0.1 mL |
| Regulatory Status |
RUO |
| Research Discipline |
Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors |
| Primary or Secondary |
Primary |
| Test Specificity |
This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity. |
| Target Species |
Human, Rat |
| Content And Storage |
Store at 4°C in the dark. |
| Isotype |
IgG |
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