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CD34 Antibody (HPCA1/1806R), DyLight 594, Novus Biologicals™
SDP

Catalog No. NB008083 Shop All R&D Systems Products
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NB008083 0.1 mL
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Catalog No. NB008083 Supplier Novus Biologicals Supplier No. NBP254355DL594
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Rabbit Monoclonal Antibody

CD34 Monoclonal specifically detects CD34 in Human, Rat samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen CD34
Applications Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone HPCA1/1806R
Conjugate DyLight 594
Dilution Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Gene Symbols CD34
Host Species Rabbit
Immunogen Recombinant full-length human CD34 protein (Uniprot: P28906)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors
Primary or Secondary Primary
Test Specificity This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.
Target Species Human, Rat
Content And Storage Store at 4°C in the dark.
Isotype IgG
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