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CD34 Antibody (QBEnd/10 + HPCA1/763), FITC, Novus Biologicals™
SDP

Catalog No. NB007516 Shop All R&D Systems Products
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NB007516 0.1 mL
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Catalog No. NB007516 Supplier Novus Biologicals Supplier No. NBP247909F
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Description

Mouse Monoclonal Antibody

CD34 Monoclonal specifically detects CD34 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Proximity Ligation Assay, Immunofluorescence.

Specifications

Antigen CD34
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone QBEnd/10 + HPCA1/763
Conjugate FITC
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation PBS with 0.05% Sodium Azide
Gene Alias CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Gene Symbols CD34
Host Species Mouse
Immunogen Detergent solubilized vesicular suspension prepared from human term placenta (QBEnd/10); Recombinant full-length human CD34 protein (CD34/763) (Uniprot: P28906)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors
Primary or Secondary Primary
Test Specificity This monoclonal antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 λ
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