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CD34 Mouse anti-Human, FITC, Clone: 581, BD

Mouse Monoclonal Antibody

$138.60 - $263.50

Specifications

Antigen CD34
Clone 581
Applications Flow Cytometry
Classification Monoclonal
Conjugate FITC
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB560942
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BD Biosciences
560942
25 Tests
Each for $138.60
Only null left
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BDB555821
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BD Biosciences
555821
100 Tests
Each for $263.50
Only null left
Add to Cart
 
Description

Description

The 581 monoclonal antibody specifically binds to CD34, a sialomucin-like type I transmembrane glycoprotein. This single-chain, 105-120 kDa, heavily O-glycosylated protein is expressed on hematopoietic progenitor cells, vascular endothelium, bone marrow stromal cells and embryonic fibroblasts. The cytoplasmic region of the CD34 antigen is a target for phosphorylation by activated protein kinase C suggesting CD34 may play a role in signal transduction. CD34 may also play a role as an adhesion molecule since it binds to CD62E and CD62L. Clone 581 binds to the class III CD34 epitope, it is resistant to neuraminidase, chymopapain and glycoprotease. The 581 antibody blocks reactivity of another anti-CD34 monoclonal antibody, 8G12.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

Specifications

CD34
Flow Cytometry
FITC
RUO
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
581
Monoclonal
Mouse
Human
IgG1 κ
Affinity Purified
gp105-120; My10; Hematopoietic progenitor cell antigen CD34
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