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CD37 Antibody (IPO-24), Novus Biologicals™
SDP

Catalog No. NBP24475000 Shop All R&D Systems Products
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NBP24475000 0.02 mg
NBP24475001 0.1 mg
NBP24475002 0.2 mg
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Catalog No. NBP24475000 Supplier Novus Biologicals Supplier No. NBP2447500.02MG
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Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

CD37 Monoclonal specifically detects CD37 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Functional, Immunofluorescence.

Specifications

Antigen CD37
Applications Flow Cytometry, SDS-Page, Immunofluorescence
Classification Monoclonal
Clone IPO-24
Concentration 0.2 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias CD37 antigentetraspanin-26, CD37 molecule, cell differentiation antigen 37, GP52-40, leukocyte antigen CD37, MGC120234, Tetraspanin-26, Tspan-26, TSPAN26leukocyte surface antigen CD37
Gene Symbols CD37
Host Species Mouse
Immunogen Spleen cells of a patient with hairy cell leukemia
Purification Method Protein A or G purified
Quantity 0.02 mg
Regulatory Status RUO
Research Discipline Cellular Markers, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 951
Test Specificity Recognizes a protein of 33-55kDa, identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin's lymphoma (B-NHL).
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG2b κ
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