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CD43/Sialophorin Antibody (SPN/1094), Alexa Fluor™ 594, Novus Biologicals™
SDP

Catalog No. NP247880A94 Shop All R&D Systems Products
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NP247880A94 0.1 mL
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Catalog No. NP247880A94 Supplier Novus Biologicals Supplier No. NBP247880AF594
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Description

Mouse Monoclonal Antibody

CD43/Sialophorin Monoclonal specifically detects CD43/Sialophorin in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen CD43/Sialophorin
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone SPN/1094
Conjugate Alexa Fluor 594
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias CD43 antigen, CD43), Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, sialophorin (gpL115, leukosialin, CD43)
Gene Symbols SPN
Host Species Mouse
Immunogen Recombinant full-length human CD43/Sialophorin protein (Uniprot: P16150)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 6693
Test Specificity It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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