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Invitrogen™ CD44var (v10) Monoclonal Antibody (VFF-14), eBioscience™
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Catalog No. 5017761
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100 μg
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50-177-61 100 μg
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Catalog No. 50-177-61 Supplier Invitrogen™ Supplier No. BMS119
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Description

Mouse Monoclonal Antibody

Description: Specifically recognizes an epitope encoded by exon v10 on the variant portion of human CD44. Standard CD44 (CD44s) lacks the entire variable region and is found mainly in cells of lymphohematopoietic origin. The multiple isoforms (designated CD44v; v = variant) contain alternatively spliced exons inserted within the extracellular domain. These isoforms are known as CD44v1, CD44v2, CD44v3, CD44v4, CD44v5, CD44v6, CD44v7, CD44v8, CD44v9, CD44v10, CD44v11. Applications Tested: Western Blot. Purity: >95%.

CD44 cell surface antigen is a 100kDa glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.
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Specifications

Antigen CD44var (v10)
Applications Western Blot
Classification Monoclonal
Clone VFF-14
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CD44
Gene Accession No. P16070
Gene Alias AL133330.1; AU023126; AW121933; AW146109; Cd44; CD44 antigen; CD44 molecule (Indian blood group); CD44 splice variant; CD44 var; CD44 variant; CD44A; CD44v10; CDw44; cell surface glycoprotein CD44; Cell surface glycoprotein CD44 (hyaluronate binding protein); chondroitin sulfate proteoglycan 8; CSPG8; ECMRIII; ECMR-III; epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; H-CAM v10; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; HERMES; Hermes antigen; homing function and Indian blood group system; HUTCHI; HUTCH-I; Hyaluronate receptor; IN; LHR; Ly-24; Lymphocyte antigen 24; MC56; MDU2; MDU3; METAA; MGC10468; MIC4; MUTCH-I; PGP I; Pgp1; PGP-1; PGP-I; phagocytic glycoprotein 1; Phagocytic glycoprotein I; RHAMM; soluble CD44
Gene Symbols CD44
Host Species Mouse
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 960
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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