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CD49e (Integrin alpha 5) Monoclonal Antibody (eBioSAM-1 (SAM-1, SAM1)), eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
$1562.00
Specifications
Antigen | CD49e (Integrin alpha 5) |
---|---|
Clone | eBioSAM-1 (SAM-1, SAM1) |
Concentration | 0.5 mg/mL |
Applications | Flow Cytometry, Immunohistochemistry, Immunoprecipitation |
Classification | Monoclonal |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
14-049-637
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Invitrogen™
14049637 |
2 mg |
Each of 1 for $1,562.00
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Description
The eBioSAM-1 MAb reacts with human integrin alpha 5, also known as fibronectin receptor alpha chain, very late activation antigen 5 alpha, and CD49e. Integrins are composed of an alpha chain and a beta chain, which non-covalently associate to form the functional integrin. Integrin heterodimers participate in cell surface-mediated signaling and adhesion functions. Integrin alpha 5 undergoes post-translational cleavage in its extracellular domain to yield disulfide linked light and heavy chains that join with Integrin beta 1 (CD29) to form the fibronectin receptor, also known as the very late activation antigen-5 (VLA-5) complex. Integrin alpha 5 is expressed on thymocytes, T cells, monocytes, platelets, early B cells, and activated B cells.
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.Specifications
CD49e (Integrin alpha 5) | |
0.5 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.09% sodium azide; pH 7.2 | |
3678 | |
Primary | |
4°C | |
Itga5 |
eBioSAM-1 (SAM-1, SAM1) | |
Flow Cytometry, Immunohistochemistry, Immunoprecipitation | |
Unconjugated | |
Mouse | |
Human | |
P08648 | |
IgG2b | |
Affinity chromatography | |
Antibody |
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