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CD5 Antibody (C5/473 + CD5/54/F6), Novus Biologicals™
SDP

Catalog No. NBP234316F Shop All R&D Systems Products
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0.1 mg
0.2 mg
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Catalog No. Quantity
NBP234316F 0.02 mg
NBP234316A 0.1 mg
NBP234316B 0.2 mg
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Catalog No. NBP234316F Supplier Novus Biologicals Supplier No. NBP2343160.02MG
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Description

Mouse Monoclonal Antibody

CD5 Monoclonal specifically detects CD5 in Human, Rat, Bovine, Rabbit samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen CD5
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone C5/473 + CD5/54/F6
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P06127
Gene Alias CD5 antigen, CD5 antigen (p56-62), CD5 molecule, LEU1T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, T1
Gene Symbols CD5
Host Species Mouse
Immunogen Human CD5 recombinant protein (C5/473); A synthetic peptide from the intracellular region of human CD5 (CD5/54/F6)
Molecular Weight of Antigen 67 kDa
Purification Method Protein A purified
Quantity 0.02 mg
Regulatory Status RUO
Research Discipline Adaptive Immunity, Cell Biology, Cytokine Research, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 921
Test Specificity Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (∼10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG
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