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CD5 Mouse anti-Human, Clone: B-B8, Novus Biologicals™
SDP

Catalog No. NBP247981B Shop All R&D Systems Products
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0.2 mg
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NBP247981B 0.2 mg
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Catalog No. NBP247981B Supplier Novus Biologicals Supplier No. NBP2479810.2MG

Description

Mouse Monoclonal Antibody

CD5 Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

Antigen CD5
Applications Flow Cytometry, Immunofluorescence, CyTOF
Classification Monoclonal
Clone B-B8
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias CD5 antigen, CD5 antigen (p56-62), CD5 molecule, LEU1T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, T1
Gene Symbols CD5
Host Species Mouse
Immunogen T cells activated with PHA
Molecular Weight of Antigen 67 kDa
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cytokine Research, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 921
Test Specificity Recognizes a 67kDa transmembrane protein which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (∼10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Note that this MAb is not suitable for frozen tissues.
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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