| Antigen |
CD5 |
| Applications |
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin) |
| Classification |
Monoclonal |
| Clone |
CD5/54/F6 |
| Conjugate |
Unconjugated |
| Dilution |
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, SDS-Page |
| Formulation |
PBS with 0.05% BSA. with 0.05% Sodium Azide |
| Gene Accession No. |
P06127 |
| Gene Alias |
CD5 antigen, CD5 antigen (p56-62), CD5 molecule, LEU1T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, T1 |
| Gene Symbols |
CD5 |
| Host Species |
Mouse |
| Immunogen |
A synthetic peptide from the intracellular region of human CD5 |
| Molecular Weight of Antigen |
67 kDa |
| Purification Method |
Protein A purified |
| Quantity |
0.02 mg |
| Regulatory Status |
RUO |
| Research Discipline |
Adaptive Immunity, Cell Biology, Cytokine Research, Immunology, Phospho Specific |
| Primary or Secondary |
Primary |
| Gene ID (Entrez) |
921 |
| Test Specificity |
Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (∼10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes. |
| Target Species |
Human, Rat, Pig, Bovine, Chicken, Equine, Guinea Pig, Monkey, Rabbit |
| Content And Storage |
Store at 4C. |
| Form |
Purified |
| Isotype |
IgG1 κ |
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