CD64 Monoclonal Antibody (10.1), eFluor™ 450, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-255-0811	Invitrogen™ 48064941	25 Tests
48-064-942	Invitrogen™ 48064942	100 Tests

Description

Description: The 10.1 monoclonal antibody reacts with human CD64 (FcRI), a 75 kDa type I transmembrane protein. CD64 is the high affinity receptor for IgG and is involved in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, and regulation of cytokine production. Monocytes and macrophages express CD64, while mature granulocytes and lymphocytes are negative. Applications Reported: This 10.1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 10.1 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. eFluor 450 is an alternative to Pacific Blue. eFluor 450 emits at 446 nm and is excited with the violet laser line (405 nm). Please make sure that your instrument is capable of detecting this fluorochrome. Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser

CD64 (FCGR1A) encodes a protein that plays an important role in the immune response. CD64 is a high-affinity Fc-gamma receptor and is one of three related gene family members located on chromosome 1. CD64 plays an important role in the immune response and its dysfunction has been studied in cervical adenitis and tetrasomy 21.

Specifications

• Antigen: CD64
• Concentration: 5 μL/Test
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
• Gene Alias: AI323638; AV092959; CD64; CD64 antigen; CD64A; Fc fragment of IgG high affinity Ib receptor; Fc fragment of IgG receptor Ia; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc fragment of IgG, high affinity Ib, receptor for (CD64); Fc gamma receptor; Fc gamma receptor Ia; Fc receptor, IgG, high affinity I; Fcg1; Fc-gamma receptor 1; Fc-gamma receptor I A1; Fc-gamma RI; Fc-gamma RIA; FcgammaRI; FcgammaRIa; Fcgr1; FCGR1A; Fcgr1b; FcgRI; FCRI; FLJ18345; high affinity IgG Fc receptor, subunit beta; high affinity immunoglobulin gamma Fc receptor I; high-affinity immunoglobulin gamma Fc receptor I; IGFR1; IgG Fc receptor I; IgG high affinity Fc receptor; IGGHAFC; RP11-196G18.2
• Gene Symbols: FCGR1A
• Primary or Secondary: Primary
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Gene: FCGR1A

• Clone: 10.1
• Applications: Flow Cytometry
• Conjugate: eFluor 450
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P12314
• Gene ID (Entrez): 2209
• Isotype: IgG1 κ
• Purification Method: Affinity chromatography
• Product Type: Antibody