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CD68 Monoclonal Antibody (OTI3B6), TrueMAB™, OriGene
SDP

Catalog No. p-200015461
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100 μL
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50-167-9506 100 μL
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Catalog No. 50-167-9506 Supplier OriGene Supplier No. TA802949
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Description

Mouse Monoclonal Antibody

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predomitly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human maligcies, including several Acute Myeloid Leukemia studies.

Specifications

Antigen CD68
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3B6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene CD68
Gene Accession No. P34810
Gene Alias GP110, LAMP4, SCARD1
Gene Symbols CD68
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 22-319 of human CD68 produced in SF9 cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 968
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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