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CD68/SR-D1 Antibody (KP1 + C68/684), Alexa Fluor™ 532, Novus Biologicals™
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Catalog No. NP234662A32 Shop All R&D Systems Products
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NP234662A32 0.1 mL
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Catalog No. NP234662A32 Supplier Novus Biologicals Supplier No. NBP234662AF532
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Description

Mouse Monoclonal Antibody

CD68/SR-D1 Monoclonal specifically detects CD68/SR-D1 in Human, Mouse, Rat, Feline, Monkey samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Intracellular).

Specifications

Antigen CD68/SR-D1
Applications Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone KP1 + C68/684
Conjugate Alexa Fluor 532
Dilution Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular)
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias CD68 antigenmacrophage antigen CD68, CD68 molecule, DKFZp686M18236, GP110, macrosialin, SCARD1, scavenger receptor class D, member 1
Gene Symbols CD68
Host Species Mouse
Immunogen This CD68/SR-D1 Antibody (KP1 + C68/684) was developed against subcellular fraction of human alveolar macrophages (KP1); Recombinant human CD68 protein (C68/684).
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Cell Biology, Cytokine Research, Immunology, Microglia Markers
Primary or Secondary Primary
Gene ID (Entrez) 968
Test Specificity This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.
Target Species Human, Feline, Primate, Rat
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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