CD7 Antibody (T3-3A1), Allophycocyanin, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP254901APC

Catalog No. NB008467

Description

CD7 Monoclonal specifically detects CD7 in Human samples. It is validated for Flow Cytometry.

Specifications

• Antigen: CD7
• Classification: Monoclonal
• Conjugate: APC
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: CD7
• Immunogen: Human T cells
• Quantity: 0.1 mL
• Research Discipline: Cytokine Research, Signal Transduction
• Test Specificity: Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
• Content And Storage: Store at 4°C in the dark.

• Applications: Flow Cytometry
• Clone: T3-3A1
• Dilution: Flow Cytometry
• Gene Alias: CD7 antigen, CD7 antigen (p41), CD7 molecule, GP40T-cell surface antigen Leu-9, LEU-9, T-cell antigen CD7, T-cell leukemia antigen, Tp40, TP41p41 protein
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Isotype: IgG1 κ