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CD7 Antibody (T3-3A1), Janelia Fluor™ 549, Novus Biologicals™
SDP

Catalog No. NB008475 Shop All R&D Systems Products
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NB008475 0.1 mL
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Catalog No. NB008475 Supplier Novus Biologicals Supplier No. NBP254901JF549
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Description

Mouse Monoclonal Antibody

CD7 Monoclonal specifically detects CD7 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Specifications

Antigen CD7
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone T3-3A1
Conjugate Janelia Fluor 549
Dilution Flow Cytometry, Immunofluorescence
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias CD7 antigen, CD7 antigen (p41), CD7 molecule, GP40T-cell surface antigen Leu-9, LEU-9, T-cell antigen CD7, T-cell leukemia antigen, Tp40, TP41p41 protein
Gene Symbols CD7
Host Species Mouse
Immunogen Human T cells
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cytokine Research, Signal Transduction
Primary or Secondary Primary
Test Specificity Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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