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CD7 Mouse anti-Human, Clone: T3-3A1, Novus Biologicals™
SDP

Catalog No. NBP25490102 Shop All R&D Systems Products
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0.2 mg
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NBP25490102 0.2 mg
NBP25490101 0.1 mg
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Catalog No. NBP25490102 Supplier Novus Biologicals Supplier No. NBP2549010.2MG

Description

Mouse Monoclonal Antibody

CD7 Monoclonal antibody specifically detects CD7 in Human samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

Antigen CD7
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone T3-3A1
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Formulation 10mM PBS with No Preservative
Gene Alias CD7 antigen, CD7 antigen (p41), CD7 molecule, GP40T-cell surface antigen Leu-9, LEU-9, T-cell antigen CD7, T-cell leukemia antigen, Tp40, TP41p41 protein
Gene Symbols CD7
Host Species Mouse
Immunogen Human T cells
Molecular Weight of Antigen 40 kDa
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Cytokine Research, Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 924
Test Specificity Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Target Species Human
Content And Storage Store at 4°C.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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