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  6. Invitrogen™ CD70 Monoclonal Antibody (FR70), PE, eBioscience™, Invitrogen™ 

Invitrogen™ CD70 Monoclonal Antibody (FR70), PE, eBioscience™, Invitrogen™

Catalog No. p-7068852
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50-104-63 50 μg
50-104-64 100 μg
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Catalog No. 50-104-63 Supplier Invitrogen™ Supplier No. 12070181
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Description

Rat Monoclonal Antibody

Description: The FR70 monoclonal antibody reacts with mouse CD70, a 30-33 kDa type II transmembrane glycoprotein. CD70 is a member of the TNF family and is expressed by activated mouse T and B lymphocytes. Interaction of CD70 with CD27, its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation. Applications Reported: This FR70 antibody has been reported for use in flow cytometric analysis. Applications Tested: This FR70 antibody has been tested by flow cytometric analysis of LPS-stimulated mouse splenocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD70
Applications Flow Cytometry
Classification Monoclonal
Clone FR70
Concentration 0.2 mg/mL
Conjugate PE
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Cd70
Gene Accession No. O55237
Gene Alias CD27 ligand; Cd27l; CD27-L; CD27LG; CD70; CD70 antigen; Cd70 molecule; Ki-24 antigen; surface antigen CD70; Tnfsf7; TNLG8A; tumor necrosis factor (ligand) superfamily, member 7; tumor necrosis factor ligand 8A; tumor necrosis factor ligand superfamily member 7
Gene Symbols Cd70
Host Species Rat
Purification Method Affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21948
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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