CD74 Antibody (LN-2), Alexa Fluor™ 350, Novus Biologicals™

Catalog No.	Quantity
NP233088A30	0.1 mL

Catalog No. NP233088A30 Supplier Novus Biologicals Supplier No. NBP233088AF350

Description

Mouse Monoclonal Antibody

CD74 Monoclonal specifically detects CD74 in Human, Mouse, Baboon, Rat (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: CD74
• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: LN-2
• Conjugate: Alexa Fluor 350
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Alias: CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, classII antigen-associated), CD74 molecule, major histocompatibility complex, class II invariant chain, DHLAGgamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia antigen-associated invariant chain, Ia-associated invariant chain, Ia-GAMMA, Ii, MHC HLA-DR gamma chain, p33
• Gene Symbols: CD74
• Host Species: Mouse
• Immunogen: SU-DHL-4 lymphoma cells were used as the immunogen for the CD74 antibody
• Purification Method: Protein A or G purified
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Gene ID (Entrez): 972
• Test Specificity: It recognizes a protein of ∼35kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
• Target Species: Human, Mouse, Baboon, Rat
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG1 κ