CD79A Antibody (IGA/1790R), Novus Biologicals™

Catalog No.	Quantity
NB413832	100 μg
NBP254608	20 μg

Catalog No. NB413832 Supplier Novus Biologicals Supplier No. NBP254608100UG

Description

Rabbit Monoclonal Antibody

CD79A Monoclonal specifically detects CD79A in Human, Mouse, Rat, Porcine, Bovine, Monkey samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array.

Specifications

• Antigen: CD79A
• Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array
• Classification: Monoclonal
• Clone: IGA/1790R
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Dilution: Western Blot 0.5-1 μg/mL, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin 1-2 μg/mL, Protein Array
• Formulation: Prepared in 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
• Gene Accession No.: P11912
• Gene Alias: CD79a antigen, CD79A antigen (immunoglobulin-associated alpha), CD79a molecule, immunoglobulin-associated alpha, IGAB-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB1, MB-1, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein
• Gene Symbols: CD79A
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79A protein. (Uniprot: P11912)
• Molecular Weight of Antigen: 44 kDa
• Purification Method: Protein A purified
• Quantity: 100 μg
• Primary or Secondary: Primary
• Gene ID (Entrez): 973.0
• Test Specificity: A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.
• Target Species: Human, Mouse, Rat, Pig, Bovine, Monkey
• Content And Storage: Store at 4°C.
• Form: Purified
• Isotype: IgG