CD79A Antibody (IGA/515), Alexa Fluor™ 532, Novus Biologicals™

Catalog No.	Quantity
NP247839A32	0.1 mL

Catalog No. NP247839A32 Supplier Novus Biologicals Supplier No. NBP247839AF532

Description

Mouse Monoclonal Antibody

CD79A Monoclonal specifically detects CD79A in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

• Antigen: CD79A
• Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
• Classification: Monoclonal
• Clone: IGA/515
• Conjugate: Alexa Fluor 532
• Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Alias: CD79a antigen, CD79A antigen (immunoglobulin-associated alpha), CD79a molecule, immunoglobulin-associated alpha, IGAB-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB1, MB-1, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein
• Gene Symbols: CD79A
• Host Species: Mouse
• Immunogen: Recombinant full-length human IGA protein
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Gene ID (Entrez): 973
• Test Specificity: A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.
• Target Species: Human
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG1 κ