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CD81 Antibody (1.3.3.22), PE/Atto594, Novus Biologicals™
SDP

Catalog No. N254548P594 Shop All R&D Systems Products
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N254548P594 0.1 mL
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Catalog No. N254548P594 Supplier Novus Biologicals Supplier No. NBP254548PEATT594
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Description

Mouse Monoclonal Antibody

CD81 Monoclonal specifically detects CD81 in Human, Mouse, Rat samples. It is validated for Flow Cytometry, Flow (Cell Surface), Knockout Validated.

Specifications

Antigen CD81
Applications Flow Cytometry, Immunoassay
Classification Monoclonal
Clone 1.3.3.22
Conjugate PE/ATTO 594
Dilution Flow Cytometry, Flow (Cell Surface), Knockout Validated
Formulation PBS with 0.05% Sodium Azide
Gene Alias CD81 antigen, CD81 antigen (target of antiproliferative 1), CD81 molecule, CVID6, TAPA1, TAPA-1, Target of the antiproliferative 1, Tetraspanin-28, Tspan-28, tspan-28,26 kDa cell surface protein TAPA-1, TSPAN28S5.7
Gene Symbols CD81
Host Species Mouse
Immunogen Recombinant full-length human CD81 protein (Uniprot: P60033)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Adaptive Immunity, Cell Cycle and Replication, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 975.0
Test Specificity Recognizes a protein of 26kDa, identified as CD81 (Workshop VI; Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C in the dark. Do not freeze.
Isotype IgG1 κ
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