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CD8b Monoclonal Antibody (SIDI8BEE), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
$413.00
Specifications
| Antigen | CD8b |
|---|---|
| Clone | SIDI8BEE |
| Concentration | 5 μL/Test |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
46-527-342
|
Invitrogen™
46527342 |
100 Tests |
Each of 1 for $413.00
|
|
|||||
Description
The SIDI8BEE monoclonal antibody reacts with human and rhesus macaque CD8 beta. The CD8b chain associates with the CD8a chain to form the CD8ab heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.Specifications
| CD8b | |
| 5 μL/Test | |
| Monoclonal | |
| Liquid | |
| RUO | |
| P10966 | |
| IgG1 κ | |
| 4°C, store in dark, DO NOT FREEZE! |
| SIDI8BEE | |
| Flow Cytometry | |
| PerCP-eFluor 710 | |
| Mouse | |
| Human, Monkey | |
| 926 | |
| Primary | |
| Antibody |
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