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CD99 Antibody (MIC2/877), PE/Atto594, Novus Biologicals™
SDP

Catalog No. N247895P594 Shop All R&D Systems Products
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N247895P594 0.1 mL
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Catalog No. N247895P594 Supplier Novus Biologicals Supplier No. NBP247895PEATT594
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Description

Mouse Monoclonal Antibody

CD99 Monoclonal specifically detects CD99 in Human, Rat (Negative) samples. It is validated for Flow Cytometry.

Specifications

Antigen CD99
Applications Flow Cytometry
Classification Monoclonal
Clone MIC2/877
Conjugate PE/ATTO 594
Dilution Flow Cytometry
Formulation PBS with 0.05% Sodium Azide
Gene Alias 12E7, CD99 antigenY homolog, CD99 molecule, E2 antigen, HBA71, MIC2 (monoclonal 12E7), MIC2Y, MSK5X, Protein MIC2, surface antigen MIC2, T-cell surface glycoprotein E2
Gene Symbols CD99
Host Species Mouse
Immunogen Recombinant full-length human CD99 protein (Uniprot: P14209)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Immunology
Primary or Secondary Primary
Gene ID (Entrez) 4267.0
Test Specificity Recognizes a sialoglycoprotein of 27-32kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32kDa (p30/32).Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis.CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing s sarcoma cells and primitive peripheral neuroectodermal tumors.
Target Species Human, Rat (Negative)
Content And Storage Store at 4°C in the dark. Do not freeze.
Isotype IgG1 κ
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