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CDC2/CDK1 Mouse, Clone: POH-1; same as cdc2.1, Novus Biologicals™
SDP

Catalog No. NBP234331F Shop All R&D Systems Products
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NBP234331F 0.02 mg
NBP234331A 0.1 mg
NBP234331B 0.2 mg
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Catalog No. NBP234331F Supplier Novus Biologicals Supplier No. NBP2343310.02MG
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Description

Mouse Monoclonal Antibody

CDC2/CDK1 Monoclonal specifically detects CDC2/CDK1 in Human, Bovine, Mink, Mustelid, Monkey, Drosophila (Negative), Mouse (Negative), Rat (Negative), Xenopus (Negative) samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen CDC2/CDK1
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone POH-1; same as cdc2.1
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen 1-2ug/ml, SDS-Page
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P06493
Gene Alias CDC28A, CDC2MGC111195, cell cycle controller CDC2, Cell division control protein 2 homolog, Cell division protein kinase 1, cyclin-dependent kinase 1, DKFZp686L20222, EC 2.7.11.22, EC 2.7.11.23, G1 to S and G2 to M, p34 protein kinase, P34CDC2
Gene Symbols CDK1
Host Species Mouse
Immunogen Purified recombinant human p34cdc2 fusion protein
Molecular Weight of Antigen 34 kDa
Purification Method Protein A purified
Quantity 0.02 mg
Regulatory Status RUO
Research Discipline Breast Cancer, Cancer, Cell Cycle and Replication, Core ESC Like Genes, Mitotic Regulators, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 983
Test Specificity Recognizes a 34kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. cdk1/ p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated cdk1/ p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.
Target Species Human, Bovine, Mustelid, Primate, Drosophila (Negative), Mouse (Negative), Rat (Negative), Xenopus (Negative)
Content And Storage Store at 4C.
Form Purified
Isotype IgG2a κ
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