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CDC37 Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Encompass_Preferred

$395.30

Specifications

Antigen CDC37
Concentration 0.2 mg/mL
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Conjugate Unconjugated
Format Liquid
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-172-6123
Encompass_Preferred
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Proteintech Group IncSupplier Diversity Partner
102181AP150UL
150 μL
Each for $395.30
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Description

Description

In S. cerevisiae, Cdc37 has been shown to be an important regulator of cell division cycle through its action on cyclin-dependent kinases (CDK′s). Cdc37 has also been associated with signaling pathways and kinases unrelated to cell cycle control, including v-Src, casein kinase II, MPS1 kinase and the sevenless receptor tyrosine kinase. Interestingly, HSP90 has also been shown to be associated with many of the same cellular targets as Cdc37. It has now been shown that Cdc37 is the same protein previously described as p50 which has been found to be associated with many of the same proteins as HSP90. Among others, Cdc37/p50 has been found complexed with Src-family kinases (Fyn, Yes, Fes, Lck and Fgr), Raf and pp60v-src. More recently, Cdc37 has been shown to be a chaperone independently and in concert with HSP90. In fact, Cdc37 is necessary for the binding of HSP90 to Cdk4.
Specifications

Specifications

CDC37
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Polyclonal
-20°C
0.2 mg/mL
Unconjugated
Rabbit
Human, Mouse, Non-human Primate, Rat
IgG
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications
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