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CDw17 Antibody (HO18.3G-6.F5), Novus Biologicals™
Mouse Monoclonal Antibody
$243.50 - $487.50
Specifications
| Antigen | CDw17 |
|---|---|
| Clone | HO18.3G-6.F5 |
| Concentration | 0.2 mg/mL |
| Dilution | Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml |
| Applications | Flow Cytometry, Immunofluorescence |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
NBP24527900
|
Novus Biologicals
NBP2452790.02MG |
0.02 mg |
Each for $243.50
|
|
|||||
|
NBP24527901
|
Novus Biologicals
NBP2452790.1MG |
0.1 mg |
Each for $487.50
|
|
|||||
|
NBP24527902
|
Novus Biologicals
NBP2452790.2MG |
0.2 mg | N/A | N/A | N/A | ||||
Description
Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence
CDw17 Monoclonal specifically detects CDw17 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.Specifications
| CDw17 | |
| 0.2 mg/mL | |
| Flow Cytometry, Immunofluorescence | |
| Unconjugated | |
| Mouse | |
| Human | |
| 8869 | |
| B-2 Microglobulin associated proteins from a detergent lysate of human PBL | |
| Primary | |
| Store at 4C. |
| HO18.3G-6.F5 | |
| Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml | |
| Monoclonal | |
| Purified | |
| RUO | |
| 10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
| ST3GAL5 | |
| IgM | |
| Protein A or G purified | |
| CD17 is an intermediate glycosphingolipid from the metabolism of higher gangliosides that localizes to sphingolipid-sterol rafts. CD17 is detectable in monocytes, granulocytes, basophils, platelets, a subset of peripheral B cells (CD19+) and tonsil dendritic cells. It is rapidly down regulated on activated granulocytes and is upregulated on IL-2 activated T lymphocytes. CD17 binds to bacteria and may function in phagocytosis. VEGF-treated endothelial cells can produce CD17, which can then mediate signaling toward PECAM-1 expression and angiogenesis. Tumor necrosis factor alpha (TNFalpha)-induced astrogliosis (astrocyte proliferation and glial fibrillary acidic protein (GFAP) upregulation) in response to neuro-inflammation (i.e. spinal cord injury) causes an increase in intracellular levels of CD17. Aberrant levels of glycosphingolipids are a feature of cancer cells and may influence integrin clustering and internalization. |
For Research Use Only
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