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CDX2 Antibody (PCRP-CDX2-1A3), DyLight 755, Novus Biologicals™
SDP

Catalog No. NB008932 Shop All R&D Systems Products
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NB008932 0.1 mL
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Catalog No. NB008932 Supplier Novus Biologicals Supplier No. NBP275759IR
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Description

Mouse Monoclonal Antibody

CDX2 Monoclonal specifically detects CDX2 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen CDX2
Applications Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone PCRP-CDX2-1A3
Conjugate DyLight 755
Dilution Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2
Gene Symbols CDX2
Host Species Mouse
Immunogen Recombinant human full-length CDX2 protein (Uniprot: Q99626)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators
Primary or Secondary Primary
Test Specificity The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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