Invitrogen™ CEACAM1/CEACAM5 Recombinant Rabbit Monoclonal Antibody (BLR032F)

Rabbit Recombinant Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA544259	Invitrogen™ MA544259	100 μL
PIMA544260	Invitrogen™ MA544260	10 μL

Description

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker CEACAM1 expression is down-regulated in many tumors indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

Specifications

• Antigen: CEACAM1/CEACAM5
• Concentration: 50 μg/mL
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
• Gene Accession No.: P06731, P13688
• Gene ID (Entrez): 1048, 634
• Immunogen: Recombinant protein representing the extracellular domain of human CEACAM1 (residues 35-433).
• Product Type: Antibody

• Clone: BLR032F
• Content And Storage: 4°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: CEACAM1
• Gene Alias: antigen CD66; BGP; BGP1; BGP-1; BGPI; Biliary glycoprotein 1; Carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); carcinoembryonic antigen-related cell adhesion molecule 5; CD66a; CD66a antigen; CD66e; CEA; CEACAM1; CEACAM5; Meconium antigen 100; pan CEACAM; sCD66e; soluble CD66e
• Gene Symbols: CEACAM1, CEACAM5
• Primary or Secondary: Primary
• Purification Method: Purified