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CEACAM5/CD66e Antibody (C66/195), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NP247973A30 Shop All R&D Systems Products
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NP247973A30 0.1 mL
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Catalog No. NP247973A30 Supplier Novus Biologicals Supplier No. NBP247973AF350
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Description

Mouse Monoclonal Antibody

CEACAM5/CD66e Monoclonal specifically detects CEACAM5/CD66e in Human, Monkey samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen CEACAM5/CD66e
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone C66/195
Conjugate Alexa Fluor 350
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias Carcinoembryonic antigen, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e antigen, CEACD66e, DKFZp781M2392, Meconium antigen 100
Gene Symbols CEACAM5
Host Species Mouse
Immunogen Purified human CEACAM5/CD66e protein (Uniprot: P06731)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 1048
Test Specificity This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This monoclonal antibody reacts with nonspecific cross-reacting antigen (NCA) and shows a cross-reaction with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbladder, urachus, salivary gland, ovary, and endocervix.
Target Species Human, Monkey
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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