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CEACAM5/CD66e Antibody (COL-1 + CEA31 + C66/261), Alexa Fluor™ 405, Novus Biologicals™
SDP

Catalog No. NBP234597W Shop All R&D Systems Products
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NBP234597W 0.1 mL
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Catalog No. NBP234597W Supplier Novus Biologicals Supplier No. NBP234597AF405
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Description

Mouse Monoclonal Antibody

CEACAM5/CD66e Monoclonal specifically detects CEACAM5/CD66e in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen CEACAM5/CD66e
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone COL-1 + CEA31 + C66/261
Conjugate Alexa Fluor 405
Dilution Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias Carcinoembryonic antigen, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e antigen, CEACD66e, DKFZp781M2392, Meconium antigen 100
Gene Symbols CEACAM5
Host Species Mouse
Immunogen Human colon carcinoma extract (COL-1 & CEA31); Recombinant full-length human CEA protein (C66/261) (Uniprot: P06731)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer, Cellular Markers, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 1048
Test Specificity This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This monoclonal antibody does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbladder, urachus, salivary gland, ovary, and endocervix.
Target Species Human
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1, IgG2a
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For Research Use Only

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