Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Cell Analysis Products
  4. Cell Based Assays
  5. General Cell Based Assays
  6. K1667

Thermo Scientific™ CellSensor™ NFkB-bla ME-180 Cell Line

Catalog No. K1667
Encompass_Preferred
Change view
Click to view available options
Quantity:
1 Vial
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
K1667 1 Vial
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. K1667 Supplier Thermo Scientific™ Supplier No. K1667
Only null left
Add to Cart
Add to Cart
Request a Quote

Description

The CellSensor™ NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably integrated into ME-180 cells.

The CellSensor™ NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably integrated into ME-180 cells. The cell line was created through fluorescence activated cell sorting (FACS) of cells responsive to stimulation of the NFκB pathway with tumor necrosis factor alpha (TNFα). The cell line was validated for DMSO tolerance, incubation time with stimulant, and substrate loading conditions. The CellSensor™ NFκB-bla ME-180 cell line responds to agonist treatment as expected from literature and can be adapted for high-throughput screening for agonists or antagonists of the NFκB pathway with compound libraries. Candidate drugs can also be tested for dose response against this cell line. Academic and non-profit customers, please inquire for special pricing.

TRUSTED_SUSTAINABILITY

Specifications

Assay Entry Cell-based beta lactamase reporter gene
Cell State Dividing Cells
Content And Storage CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Product Line CellSensor
Quantity 1 Vial
Target Entry TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway
Type Cell Line
Cell Line ME-180
System Type CellSensor™
Druggable Target Signaling Pathway

For Research Use Only. Not for use in diagnostic procedures.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.