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Centrin 2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501730548 Shop All Proteintech Group Inc Products
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50-173-0548 150 μL
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Catalog No. 50-173-0548 Supplier Proteintech Group Inc Supplier No. 158771AP150UL
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Description

Rabbit Polyclonal Antibody

The EF-hand type Ca2+-binding proteins family consists of several members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present, such as the retina and testis, express both Centrin-1 and -2, but Centrin-2 is also expressed in nondifferentiated, nonciliated retinal cells (retinoblastoma cells), liver, skeletal muscle and cardiac muscle. In these tissues, Centrin associates with the centrosomes, mitotic spindle poles and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.

Specifications

Antigen Centrin 2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.34 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CETN2
Gene Accession No. P41208, Q9R1K9
Gene Alias CALT, Caltractin isoform 1, CEN2, Centrin 2, centrin 2,centrin2, centrin, EF hand protein, 2, CETN2
Gene Symbols Cetn2
Host Species Rabbit
Immunogen Centrin 2 Fusion Protein Ag8638
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1069, 26370, 84593
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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