Centrin 2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-0548	Proteintech Group Inc 158771AP150UL	150 μL

Description

The EF-hand type Ca2+-binding proteins family consists of several members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present, such as the retina and testis, express both Centrin-1 and -2, but Centrin-2 is also expressed in nondifferentiated, nonciliated retinal cells (retinoblastoma cells), liver, skeletal muscle and cardiac muscle. In these tissues, Centrin associates with the centrosomes, mitotic spindle poles and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.

Specifications

• Antigen: Centrin 2
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P41208, Q9R1K9
• Gene ID (Entrez): 1069, 26370, 84593
• Immunogen: Centrin 2 Fusion Protein Ag8638
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CETN2

• Concentration: 0.34 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CALT, Caltractin isoform 1, CEN2, Centrin 2, centrin 2,centrin2, centrin, EF hand protein, 2, CETN2
• Gene Symbols: Cetn2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody