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Invitrogen™ CEP164 Polyclonal Antibody
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Catalog No. PIPA5106345
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PIPA5106345 100 μL
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Catalog No. PIPA5106345 Supplier Invitrogen™ Supplier No. PA5106345
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CEP164.

CEP164 was initially identified as a centrosomal protein, but other studies have indicated that it also plays a role in the formation of primary cilia, the microtubule-based sensory antennae projecting from the surface of many eukaryotic cells as well as in DNA damage response acting as a mediator protein. CEP164 interacts with both ATR and ATM, proteins that trigger a number of cellular responses including the initiation of DNA damaged-induced cell cycle checkpoints. It is phosphorylated upon replication stress, ultraviolet (UV) radiation, and ionizing radiation silencing of CEP164 significantly reduces the DNA damage-induced phosphorylation of several proteins in the DNA damage-activated signaling cascade and compromises cell survival after UV damage. At least two isoforms of CEP164 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CEP164
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CEP164
Gene Accession No. Q9UPV0
Gene Alias AI450905; BC027092; ce164; centrosomal protein 164; centrosomal protein 164kDa; centrosomal protein of 164 kDa; Cep 164; CEP164; D030051D21; KIAA1052; mKIAA1052; NPHP15; RGD1560988; RGD1561243
Gene Symbols CEP164
Host Species Rabbit
Immunogen A synthesized peptide derived from human CEP164(Accession Q9UPV0), corresponding to amino acid residues Q1333-G1383.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22897, 363055, 489389
Target Species Human, Rat, Canine
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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