CFH Monoclonal Antibody (OTI5H5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA804532

Catalog No. 50-168-0288

Description

Complement factor H1 (Complement factor H1, factor H1, CFH) is a plasma glycoprotein (139 kDa) and the secreted form of the protein is composed of 20 repetitive units of 60 amino acids, named short consensus repeats (SCR). Factor H1 is a central regulator of early alternative pathway activation by acting as a cofactor for factor I in the cleavage of C3b into iC3b. Factor H1 also competes with factor B for binding with C3b, inhibiting excessive alternative pathway activation. Complete (homozygous) factor H1 deficiency by genetic mutation has been rarely reported.

Specifications

• Antigen: CFH
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P08603
• Gene Symbols: CFH
• Immunogen: Human recombit protein fragment corresponding to amino acids 125-346 of human CFH produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: OTI5H5
• Conjugate: Unconjugated
• Gene: CFH
• Gene Alias: AHUS1, AMBP1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3075
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid