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CGP 57380, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
1mg
10mg
50mg
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522629-08-9
C11H9FN6
244.233
UQPMANVRZYYQMD-UHFFFAOYSA-N
mnk1 inhibitor,n3-4-fluorophenyl-1h-pyrazolo 3,4-d pyrimidine-3,4-diamine,4-amino-5-4-fluoroanilino-pyrazolo 3,4-d pyrimidine,d0a7fq,cgp hplc,n-4-fluorophenyl-3h-pyrazolo 3,4-d pyrimidine-3,4-diamine,3-n-4-fluorophenyl-1h-pyrazolo 3,4-d pyrimidine-3,4-diamine,3-n-4-fluorophenyl-2h-pyrazolo 3,4-d pyrimidine-3,4-diamine,n3-4-fluorophenyl-1h-pyrazolo-3,4-d pyrimidine-3,4-diamine,n3-4-fluorophenyl-2h-pyrazolo 3,4-d pyrimidine-3,4-diamine
11644425
3-N-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
C1=CC(=CC=C1NC2=C3C(=NC=NC3=NN2)N)F
This item is not returnable. View return policy
522629-08-9
C11H9FN6
244.233
UQPMANVRZYYQMD-UHFFFAOYSA-N
mnk1 inhibitor,n3-4-fluorophenyl-1h-pyrazolo 3,4-d pyrimidine-3,4-diamine,4-amino-5-4-fluoroanilino-pyrazolo 3,4-d pyrimidine,d0a7fq,cgp hplc,n-4-fluorophenyl-3h-pyrazolo 3,4-d pyrimidine-3,4-diamine,3-n-4-fluorophenyl-1h-pyrazolo 3,4-d pyrimidine-3,4-diamine,3-n-4-fluorophenyl-2h-pyrazolo 3,4-d pyrimidine-3,4-diamine,n3-4-fluorophenyl-1h-pyrazolo-3,4-d pyrimidine-3,4-diamine,n3-4-fluorophenyl-2h-pyrazolo 3,4-d pyrimidine-3,4-diamine
11644425
3-N-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
C1=CC(=CC=C1NC2=C3C(=NC=NC3=NN2)N)F

Selective inhibitor of Mnk1

Inhibitor of MAP-kinase interacting kinase-1 (Mnk1, MKNK1) (IC 50 = 2.2 μM) that displays selectivity over p38, JNK1, ERK1, ERK2, PKC and c-src family kinases. Blocks phosphorylation of eIF4E in cellular assays (IC 50 = 3 μM) and inhibits LPS-induced TNFα expression in macrophages.

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Quantity 50mg
Formula Weight 244.23
Percent Purity >98%
Chemical Name or Material CGP 57380

Recommended Storage : Store at +4°C