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  5. Tocris Bioscience™ CGP 57380

Tocris Bioscience™ CGP 57380
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Catalog No. 273150
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Quantity:
1 mg
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective inhibitor of Mnk1

Inhibitor of MAP-kinase interacting kinase-1 (Mnk1, MKNK1) (IC50 = 2.2 μM) that displays selectivity over p38, JNK1, ERK1, ERK2, PKC and c-src family kinases. Blocks phosphorylation of eIF4E in cellular assays (IC50 = 3 μM) and inhibits LPS-induced TNFα expression in macrophages.

Chemical Identifiers

CAS 522629-08-9
Molecular Formula C11H9FN6

Specifications

Quantity 50 mg
Formula Weight 244.23
Purity >98%
Molecular Weight (g/mol) 244.233
Chemical Name or Material CGP 57380

Safety and Handling

Recommended Storage Store at +4°C
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