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Description
Chlorhexidine is a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.
- It is an agent to prevent gingivitis and was used to study the effects of antimicrobials on dental plaque
- Commercial ophthalmic products have used this agent to replace thimerosal as a preservative; however, it can cause skin irritation
- It has been used to study the inactivation of HIV and the immobilization of sperm
- It was used to study effective skin antisepsis and disinfection of medical devices
Specifications
Specifications
| Melting Point | 151°C to 159°C |
| Quantity | 100 g |
| Solubility Information | Soluble in water (0.15g/10mL water with heat), in ethanol (50mg/mL - clear, faint yellow solution), alcohol, glycerol, propylene, glycol, polyethylene glycols. |
| Formula Weight | 625.56g/mol |
| Percent Purity | ≥97% |
| Concentration or Composition (by Analyte or Components) | CriticalMicelle Concentration (CMC) 0.01% (w/v, 25°C) (Lit.) |
| Physical Form | Powder |
Safety and Handling
| Recommended Storage | Store at Room Temperature (15–30°C) |
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