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Cholera Toxin Beta Antibody - BSA Free, Novus Biologicals™
SDP

Catalog No. NB10063067 Shop All R&D Systems Products
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0.5 mL
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Catalog No. Quantity
NB10063067 0.5 mL
NB017537 0.1 mL
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Catalog No. NB10063067 Supplier Novus Biologicals Supplier No. NB10063067
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Description

Rabbit Polyclonal Antibody has been used in 2 publications

Cholera Toxin Beta Polyclonal specifically detects Cholera Toxin Beta in Bacteria samples. It is validated for ELISA, Immunodiffusion, Immunohistochemistry, Immunohistochemistry (Frozen).

Specifications

Antigen Cholera Toxin Beta
Applications ELISA, Immunodiffusion, Immunohistochemistry, Immunohistochemistry (Frozen)
Classification Polyclonal
Concentration 4 mg/mL
Conjugate Unconjugated
Dilution ELISA 1:100-1:2000, Immunohistochemistry-Frozen, Immunodiffusion
Formulation Phosphate buffered saline with 0.1% Sodium Azide
Gene Alias Cholera enterotoxin B chain, Cholera enterotoxin beta chain, Cholera enterotoxin gamma chain, Cholera enterotoxin subunit B, Cholera toxin B protein, Choleragenoid, CTX B, CTXB, TOX B, toxB, VC1456
Host Species Rabbit
Immunogen Purified choleragenoid
Purification Method IgG purified
Quantity 0.5 mL
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity NB100-63067 is specific for the beta subunit of cholera toxin. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activate the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. This antibody immunoprecipitates cholera toxin in gel techniques.
Target Species Bacteria
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG
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For Research Use Only

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