Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) - IHC-Prediluted, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP248067

Catalog No. NBP248067

Description

Chorionic Gonadotropin alpha/beta (hCG) Monoclonal specifically detects Chorionic Gonadotropin alpha/beta (hCG) in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: hCG holo C2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: CGB3
• Immunogen: Purified hCG protein
• Quantity: 7 mL
• Research Discipline: Cancer
• Gene ID (Entrez): 1082
• Target Species: Human
• Form: Purified

• Applications: Immunohistochemistry (Paraffin)
• Clone: HCGab/52
• Dilution: Immunohistochemistry-Paraffin
• Gene Alias: choriogonadotropin subunit beta, CGB3, CGB5, CGB7, CGB8, chorionic gonadotropin, beta polypeptide, hCGB
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This monoclonal antibody is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ