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Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) - IHC-Prediluted, Novus Biologicals™
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Catalog No. NBP248067 Shop All R&D Systems Products
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NBP248067 7 mL
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Catalog No. NBP248067 Supplier Novus Biologicals Supplier No. NBP248067
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Description

Mouse Monoclonal Antibody

Chorionic Gonadotropin alpha/beta (hCG) Monoclonal specifically detects Chorionic Gonadotropin alpha/beta (hCG) in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen hCG holo C2
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone HCGab/52
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias choriogonadotropin subunit beta, CGB3, CGB5, CGB7, CGB8, chorionic gonadotropin, beta polypeptide, hCGB
Gene Symbols CGB3
Host Species Mouse
Immunogen Purified hCG protein
Purification Method Protein A or G purified
Quantity 7 mL
Regulatory Status RUO
Research Discipline Cancer
Primary or Secondary Primary
Gene ID (Entrez) 1082
Test Specificity This monoclonal antibody is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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