Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2453340.2MG

Catalog No. NBP24533402

Description

Ensure accurate, reproducible results in Immunohistochemistry (Paraffin)

Chorionic Gonadotropin beta Chain (hCG beta) Monoclonal antibody specifically detects Chorionic Gonadotropin beta Chain (hCG beta) in Human samples. It is validated for Immunohistochemistry-Paraffin.

Specifications

• Antigen: hCG holo C2
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Dilution: Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
• Gene Alias: choriogonadotropin subunit beta, CGB3, CGB5, CGB7, CGB8, chorionic gonadotropin, beta polypeptide, hCGB
• Immunogen: Purified hCG protein
• Quantity: 0.2 mg
• Primary or Secondary: Primary
• Test Specificity: This MAb is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin)
• Clone: HCGab/52
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Gene ID (Entrez): 1082
• Target Species: Human
• Form: Purified

For Research Use Only