Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52), Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP24533400	Novus Biologicals NBP2453340.02MG	0.02 mg
NBP24533401	Novus Biologicals NBP2453340.1MG	0.1 mg
NBP24533402	Novus Biologicals NBP2453340.2MG	0.2 mg

Description

Ensure accurate, reproducible results in Immunohistochemistry (Paraffin)

Chorionic Gonadotropin alpha/beta (hCG) Monoclonal specifically detects Chorionic Gonadotropin alpha/beta (hCG) in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: hCG holo C2
• Concentration: 0.2mg/mL
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Alias: choriogonadotropin subunit beta, CGB3, CGB5, CGB7, CGB8, chorionic gonadotropin, beta polypeptide, hCGB
• Immunogen: Purified hCG protein
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.

• Clone: HCGab/52
• Dilution: Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene ID (Entrez): 1082
• Isotype: IgG1 κ
• Purification Method: Protein A or G purified
• Test Specificity: This MAb is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.

For Research Use Only