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Chromogranin A Antibody (CHGA/765), Novus Biologicals™
SDP

Catalog No. NBP24477300 Shop All R&D Systems Products
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NBP24477300 0.02 mg
NBP24477301 0.1 mg
NBP24477302 0.2 mg
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Catalog No. NBP24477300 Supplier Novus Biologicals Supplier No. NBP2447730.02MG
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Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Chromogranin A Monoclonal specifically detects Chromogranin A in Human, Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Chromogranin A
Applications Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Classification Monoclonal
Clone CHGA/765
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Accession No. P10645
Gene Alias betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Gene Symbols CHGA
Host Species Mouse
Immunogen Recombinant human chromogranin A protein
Purification Method Protein A or G purified
Quantity 0.02 mg
Regulatory Status RUO
Research Discipline Apoptosis, Cancer, Neuronal Cell Markers, Tumor Biomarkers
Primary or Secondary Primary
Gene ID (Entrez) 1113
Test Specificity Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Target Species Human, Rat (Negative)
Content And Storage Store at 4C.
Form Purified
Isotype IgG2a κ
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For Research Use Only

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