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Chromogranin A Antibody (CHGA/777), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NP247848A30 Shop All R&D Systems Products
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NP247848A30 0.1 mL
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Catalog No. NP247848A30 Supplier Novus Biologicals Supplier No. NBP247848AF350
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Description

Mouse Monoclonal Antibody

Chromogranin A Monoclonal specifically detects Chromogranin A in Human, Rat (Negative) samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Chromogranin A
Applications Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone CHGA/777
Conjugate Alexa Fluor 350
Dilution Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Gene Symbols CHGA
Host Species Mouse
Immunogen Recombinant full-length human Chromogranin A protein (Uniprot: P10645)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 1113
Test Specificity Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Target Species Human, Rat
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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