Ciliobrevin A, Tocris Bioscience
Hedgehog (Hh) pathway antagonist, inhibits ciliogenesis; also inhibits dynein
Manufacturer: Tocris Bioscience 4529/25
DescriptionHedgehog (Hh) pathway antagonist; blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo. Perturbs primary cilia formation; inhibits cytoplasmic AAA+ ATPase dynein-dependent microtubule gliding and ATPase activity.
|Observed MW: 358.18|
Safety and Handling
Recommended Storage : Store at 4°C
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